Guinea Pig Maximization Test (gpmt) - Toxicology

Relevant Publications

PreS/MD: Predictor of Sensitization Hazard for Chemical Substances Released From Medical Devices.

Issue Release: 2022

Qualification of a non-animal vaginal irritation method admitted as nonclinical assessment model (NAM) in the Incubator Phase of the United States Food and Drug Administration (US FDA) Medical Devices Development Tool (MDDT).

Issue Release: 2019

Sensitization and cross-reactivity patterns of contact allergy to diisocyanates and corresponding amines: investigation of diphenylmethane-4,4\'-diisocyanate, diphenylmethane-4,4\'-diamine, dicyclohexylmethane-4,4\'-diisocyanate, and dicylohexylmethane-4,4\'-diamine.

Issue Release: 2017

Potential immunotoxic effects of trichloroethylene-induced IV allergic reaction in renal impairment.

Issue Release: 2017

Unsaturated fatty acids show clear elicitation responses in a modified local lymph node assay with an elicitation phase, and test positive in the direct peptide reactivity assay.

Issue Release: 2015

[Involvement of cellular immunity and humoral immunity in mixed allergy induced by trichloroethylene].

Issue Release: 2014

Sex differences in metabolism of trichloroethylene and trichloroethanol in guinea pigs.

Issue Release: 2013

Possible role of complement activation in renal impairment in trichloroethylene-sensitized guinea pigs.

Issue Release: 2012

[Changes in humoral immunity in sensitized guinea pigs exposed to trichloroethylene].

Issue Release: 2012

An assessment of the skin sensitisation hazard of a group of polyfunctional silicones using a weight of evidence approach.

Issue Release: 2012

Guinea pig sensitization assays: an experimental comparison of three methods.

Issue Release: 2011

Inter-laboratory validation of the modified murine local lymph node assay based on 5-bromo-2\'-deoxyuridine incorporation.

Issue Release: 2011

[Study on skin sensitization as well as liver and kidney impairment in guinea pigs treated with trichloroethylene].

Issue Release: 2010

Comparative testing for the identification of skin-sensitizing potentials of nonionic sugar lipid surfactants.

Issue Release: 2010

Prediction of skin sensitization with a particle swarm optimized support vector machine.

Issue Release: 2009

Quantitative structure-property relationship modeling of skin sensitization: a quantitative prediction.

Issue Release: 2009

Skin sensitization potency and cross-reactivity of p-phenylenediamine and its derivatives evaluated by non-radioactive murine local lymph node assay and guinea-pig maximization test.

Issue Release: 2009

Interlaboratory validation of the modified murine local lymph node assay based on adenosine triphosphate measurement.

Issue Release: 2008

Characterization of liver injury associated with hypersensitive skin reactions induced by trichloroethylene in the guinea pig maximization test.

Issue Release: 2008

Mercaptobenzothiazole allergenicity-role of the thiol group.

Issue Release: 2008

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Guinea Pig Maximization Test (gpmt) - Toxicology

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