Lowest Observable Adverse Effect Level (loael) - Toxicology

Relevant Publications

Pancreatic Antioxidative Defense and Heat Shock Proteins Prevent Islet of Langerhans Cell Death After Chronic Oral Exposure to Cadmium LOAEL Dose.

Issue Release: 2023

Scientific opinion on the tolerable upper intake level for selenium.

Issue Release: 2023

Sensitivity of High Conservation Value Birds to Para-Aminopropiophenone (PAPP) Determined by Sub-Lethal Dose-Response Assay.

Issue Release: 2023

Temephos, an organophosphate larvicide for residential use: a review of its toxicity.

Issue Release: 2022

Oral Subacute Exposure to Cadmium LOAEL Dose Induces Insulin Resistance and Impairment of the Hormonal and Metabolic Liver-Adipose Axis in Wistar Rats.

Issue Release: 2021

Chronic Reproductive Toxicity Thresholds for Northern Bobwhite Quail (Colinus virginianus) Exposed to Perfluorohexanoic Acid (PFHxA) and a Mixture of Perfluorooctane Sulfonic Acid (PFOS) and PFHxA.

Issue Release: 2021

Species- and Tissue-Specific Chronic Toxicity Values for Northern Bobwhite Quail (Colinus virginianus) Exposed to Perfluorohexane Sulfonic Acid and a Binary Mixture of Perfluorooctane Sulfonic Acid and Perfluorohexane Sulfonic Acid.

Issue Release: 2021

Issues in the design, analysis, and application of rodent developmental neurotoxicology studies.

Issue Release: 2021

Species-and Tissue-Specific Avian Chronic Toxicity Values (CTVs) for Perfluorooctane Sulfonate (PFOS) and a Binary Mixture of PFOS and Perfluorohexane Sulfonate.

Issue Release: 2020

Variability in studies: Defining the upper limit of performance for predictions of systemic effect levels.

Issue Release: 2020

Analysis of individual and combined estrogenic effects of bisphenol, nonylphenol and diethylstilbestrol in immature rats with mathematical models.

Issue Release: 2019

The NOAEL Metformin Dose Is Ineffective against Metabolic Disruption Induced by Chronic Cadmium Exposure in Wistar Rats.

Issue Release: 2018

Investigations on the dose-response relationship of combined exposure to low doses of three anti-androgens in Wistar rats.

Issue Release: 2017

Assessment of learning, memory, and attention in developmental neurotoxicity regulatory studies: synthesis, commentary, and recommendations.

Issue Release: 2015

Mercurial exposure of residents of Santarém and Oriximiná cities (Pará, Brazil) through fish consumption.

Issue Release: 2015

Assessing dose-response relationships for endocrine disrupting chemicals (EDCs): a focus on non-monotonicity.

Issue Release: 2015

Sea ducks and aquaculture: the cadmium connection.

Issue Release: 2010

Determination of threshold adverse effect doses of percutaneous VX exposure in African green monkeys.

Issue Release: 2010

Subchronic oral toxicity of silver nanoparticles.

Issue Release: 2010

Proposal for a revised Reference Concentration (RfC) for manganese based on recent epidemiological studies.

Issue Release: 2009

What Is the Role of Diet in Reproductive Toxicology?

Why is Transparency Important in Addressing COI?

Why is Soil Remediation Important?

How Can Polymer Toxicity Be Assessed?

What Role Do Toxicologists Play in the Superfund Program?

How do Regulations Address Mutagenic Substances?

What is Histopathology in Toxicology?

What Are the Limitations of Animal Testing?

Tomatoes: Are They Toxic?

What is a Cough in Toxicology?

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