N Acetyl P Benzoquinone Imine (napqi) - Toxicology

Relevant Publications

Paracetamol metabolism by endothelial cells - potential mechanism underlying intravenous paracetamol-induced hypotension.

Issue Release: 2024

High-Dose Acetaminophen with Concurrent CYP2E1 Inhibition Has Profound Anticancer Activity without Liver Toxicity.

Issue Release: 2024

Rutaecarpine Aggravates Acetaminophen-Induced Acute Liver Injury by Inducing CYP1A2.

Issue Release: 2024

Transcriptomic signature, bioactivity and safety of a non-hepatotoxic analgesic generating AM404 in the midbrain PAG region.

Issue Release: 2024

Transcriptomic signature, bioactivity and safety of a non-hepatoxic analgesic generating AM404 in the mid-brain PAG region.

Issue Release: 2023

High-resolution mass spectrometry identifies delayed biomarkers for improved precision in acetaminophen/paracetamol human biomonitoring.

Issue Release: 2023

A Biomimetic Nanoparticle Exerting Protection Against Acute Liver Failure by Suppressing CYP2E1 Activity and Scavenging Excessive ROS.

Issue Release: 2023

Inhibition of mitochondrial function: An alternative explanation for the antipyretic and hypothermic actions of acetaminophen.

Issue Release: 2022

Propacetamol in dogs: First description of its pharmacokinetics after intravenous and oral administration.

Issue Release: 2022

Mitochondrial versus microsomal bioactivation of paracetamol by human liver and kidney tissues.

Issue Release: 2022

Therapeutic Potential of Justicia secundaon Oxidative Stress Indices in N-Acetyl-P-Benzoquinone Imine Induced- Hepatotoxic Rats.

Issue Release: 2022

The Relationship between Prohibitin 1 Expression, Hepatotoxicity Induced by Acetaminophen, and Hepatoprotection by S-Adenosylmethionine in AML12 Cells.

Issue Release: 2022

Protective effect of probiotics against acetaminophen induced nephrotoxicity.

Issue Release: 2022

Metabolite alteration analysis of acetaminophen-induced liver injury using a mass microscope.

Issue Release: 2022

Tanshinone IIA prevents acetaminophen-induced nephrotoxicity through the activation of the Nrf2-Mrp2/4 pathway in mice.

Issue Release: 2022

Galangin Nanoparticles Protect Acetaminophen-Induced Liver Injury: A Biochemical and Histopathological Approach.

Issue Release: 2022

Analgesic Action of Acetaminophen via Kv7 Channels.

Issue Release: 2022

Progress in the treatment of drug-induced liver injury with natural products.

Issue Release: 2022

Metabolomic Evaluation of N-Acetyl-p-Benzoquinone Imine Protein Adduct Formation with Therapeutic Acetaminophen Administration: Sex-based Physiologic Differences.

Issue Release: 2022

Assessment of the biochemical pathways for acetaminophen toxicity: Implications for its carcinogenic hazard potential.

Issue Release: 2021

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