Planar Cell Polarity (pcp) Pathway - Toxicology

Relevant Publications

Wnt7b acts in concert with Wnt5a to regulate tissue elongation and planar cell polarity via noncanonical Wnt signaling.

Issue Release: 2024

The Adhesion GPCR and PCP component Flamingo (FMI-1) alters body size and regulates the composition of the extracellular matrix.

Issue Release: 2024

A vertebrate Vangl2 translational variant required for planar cell polarity.

Issue Release: 2024

Folate regulation of planar cell polarity pathway and F-actin through folate receptor alpha.

Issue Release: 2024

WNT5B promotes the malignant phenotype of non-small cell lung cancer via the FZD3-DVL3-RAC1-PCP-JNK pathway.

Issue Release: 2024

The planar cell polarity pathway is essential for optimal activity-dependent synaptic plasticity.

Issue Release: 2024

Integrated proteogenomic characterization of glioblastoma evolution.

Issue Release: 2024

Coupling and uncoupling of midline morphogenesis and cell flow in amniote gastrulation.

Issue Release: 2024

Dishevelled2 activates WGEF via its interaction with a unique internal peptide motif of the GEF.

Issue Release: 2024

Loss of the endoplasmic reticulum protein Tmem208 affects cell polarity, development, and viability.

Issue Release: 2024

Deciphering the impacts of modulating the Wnt-planar cell polarity (PCP) pathway on alveolar repair.

Issue Release: 2024

Rac1 and Nectin3 are essential for PCP-directed axon guidance in the peripheral auditory system.

Issue Release: 2024

Planar Cell Polarity Signaling: Coordinated Crosstalk for Cell Orientation.

Issue Release: 2024

Prickle2 regulates apical junction remodeling and tissue fluidity during vertebrate neurulation.

Issue Release: 2024

Loss of PRICKLE1 leads to abnormal endometrial epithelial architecture, decreased embryo implantation, and reduced fertility in mice.

Issue Release: 2024

SLMAP3 is essential for neurulation through mechanisms involving cytoskeletal elements, ABP, and PCP.

Issue Release: 2024

PDZome-wide and structural characterization of the PDZ-binding motif of VANGL2.

Issue Release: 2023

Genome-wide identification and spatiotemporal expression analysis of cadherin superfamily members in echinoderms.

Issue Release: 2023

Core PCP mutations affect short time mechanical properties but not tissue morphogenesis in the Drosophila pupal wing.

Issue Release: 2023

A complex of Wnt/planar cell polarity signaling components Vangl1 and Fzd7 drives glioblastoma multiforme malignant properties.

Issue Release: 2023

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