Recombinant Antitoxins - Toxicology

Relevant Publications

Immunization of sheep with a recombinant vaccine containing immunogenic nontoxic domains of Clostridium perfringens alpha and beta toxins.

Issue Release: 2023

Characterization of a novel tetravalent botulism antitoxin based on receptor-binding domain of BoNTs.

Issue Release: 2023

Anti-Neurotoxins from in the Development of Coral Snake Antivenoms.

Issue Release: 2022

Immunologic and Protective Properties of Subunit- vs. Whole Toxoid-Derived Anti-Botulinum Equine Antitoxin.

Issue Release: 2022

Intracellular Localization of the Proteins Encoded by Some Type II Toxin-Antitoxin Systems in Escherichia coli.

Issue Release: 2021

Potency and stability of a trivalent, catalytically inactive vaccine against botulinum neurotoxin serotypes C, E and F (triCEF).

Issue Release: 2020

The Light Chain Defines the Duration of Action of Botulinum Toxin Serotype A Subtypes.

Issue Release: 2018

An ambient temperature-stable antitoxin of nine co-formulated antibodies for botulism caused by serotypes A, B and E.

Issue Release: 2018

A Single Tri-Epitopic Antibody Virtually Recapitulates the Potency of a Combination of Three Monoclonal Antibodies in Neutralization of Botulinum Neurotoxin Serotype A.

Issue Release: 2018

A toxin-antitoxin system is essential for the stability of mosquitocidal plasmid pBsph of Lysinibacillus sphaericus.

Issue Release: 2018

Protective potential of recombinant non-purified botulinum neurotoxin serotypes C and D.

Issue Release: 2016

Isolation of nanomolar scFvs of non-human primate origin, cross-neutralizing botulinum neurotoxins A1 and A2 by targeting their heavy chain.

Issue Release: 2015

Isolation and functional characterization of the novel Clostridium botulinum neurotoxin A8 subtype.

Issue Release: 2015

Production and evaluation of a recombinant chimeric vaccine against clostridium botulinum neurotoxin types C and D.

Issue Release: 2013

The art of blocking ADP-ribosyltransferases (ARTs): nanobodies as experimental and therapeutic tools to block mammalian and toxin ARTs.

Issue Release: 2013

A novel strategy for development of recombinant antitoxin therapeutics tested in a mouse botulism model.

Issue Release: 2012

Development and preclinical evaluation of a new F(ab\')₂ antitoxin against botulinum neurotoxin serotype A.

Issue Release: 2010

Extraction and inhibition of enzymatic activity of botulinum neurotoxins/A1, /A2, and /A3 by a panel of monoclonal anti-BoNT/A antibodies.

Issue Release: 2009

A viral nanoparticle with dual function as an anthrax antitoxin and vaccine.

Issue Release: 2007

Project BioShield: what it is, why it is needed, and its accomplishments so far.

Issue Release: 2007

What is Bovine Spongiform Encephalopathy?

How Does BSE Relate to Toxicology?

What is Chromatography?

Can DNA Polymerase Be Targeted for Therapeutic Purposes?

How Are Tissue Samples Collected and Used?

What is the Role of Animal Experimentation in Toxicology?

What Causes BSE?

How are Antidepressant Overdoses Managed?

How Does TOF Mass Analyzer Work?

What is Calibration in Toxicology?

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