Udp Glucuronosyltransferase (ugt) Enzymes - Toxicology

Relevant Publications

Glucuronidation of tizoxanide, an active metabolite of nitazoxanide, in liver and small intestine: Species differences in humans, monkeys, dogs, rats, and mice and responsible UDP-glucuronosyltransferase isoforms in humans.

Issue Release: 2024

Role of microsomal metabolism in bromfenac-induced cytotoxicity.

Issue Release: 2024

Inhibition of Uridine 5\'-diphospho-glucuronosyltransferases A10 and B7 by vitamins: insights from in silico and in vitro studies.

Issue Release: 2024

In Vitro Metabolism and Transport Characteristics of Zastaprazan.

Issue Release: 2024

Anthraquinone biocolourant dermocybin is metabolized whereas dermorubin is not in in vitro liver fractions and recombinant metabolic enzymes.

Issue Release: 2024

Identification of the Biotransformation Pathways of a Potential Oral Male Contraceptive, 11β-Methyl-19-Nortestosterone (11β-MNT) and Its Prodrugs: An In Vitro Study Highlights the Contribution of Polymorphic Intestinal UGT2B17.

Issue Release: 2024

Hepatic enzyme induction and its potential effect on thyroid hormone metabolism in the metamorphosing tadpole of Xenopus laevis (African clawed frog).

Issue Release: 2024

Cytochrome P450 and UDP-glucuronosyltransferase expressions, activities, and induction abilities in 3D-cultured human renal proximal tubule epithelial cells.

Issue Release: 2024

Inhibition of human UDP-glucuronosyltransferase (UGT) enzymes by darolutamide: prediction of in vivo drug-drug interactions.

Issue Release: 2024

Cannabinoid-Induced Inhibition of Morphine Glucuronidation and the Potential for In Vivo Drug-Drug Interactions.

Issue Release: 2024

Hepatic glucuronidation of tetrabromobisphenol A and tetrachlorobisphenol A: interspecies differences in humans and laboratory animals and responsible UDP-glucuronosyltransferase isoforms in humans.

Issue Release: 2024

Metabolomic Profiling Reveals the Anti-Herbivore Mechanisms of Rice ().

Issue Release: 2024

Effects of alcohol consumption and tobacco smoking on the composition of the ensemble of drug metabolizing enzymes and transporters in human liver.

Issue Release: 2024

Drug interaction with Udp-Glucuronosyltransferase (UGT) enzymes is a predictor of drug-induced liver injury.

Issue Release: 2024

Comparison of Relative Activity versus Relative Expression Factors (RAF versus REF) in Predicting Glucuronidation Mediated Drug Clearance Using Recombinant UGTs.

Issue Release: 2024

Comparative metabolism of fargesin in human, dog, monkey, mouse, and rat hepatocytes.

Issue Release: 2023

Effect of antibiotic-administration period on hepatic bile acid profile and expression of pharmacokinetic-related proteins in mouse liver, kidney, and brain capillaries.

Issue Release: 2023

Identification of Human UDP-Glucuronosyltransferase Involved in Gypensapogenin C Glucuronidation and Species Differences.

Issue Release: 2023

Inhibition of Nicotine Metabolism by Cannabidiol (CBD) and 7-Hydroxycannabidiol (7-OH-CBD).

Issue Release: 2023

Identification of a Discrete Diglucuronide of GDC-0810 in Human Plasma after Oral Administration.

Issue Release: 2023

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Udp Glucuronosyltransferase (ugt) Enzymes - Toxicology

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