Olavi R. Pelkonen - Toxicology

Author Information

O. Pelkonen, affiliated with the Research Unit of Biomedicine/Pharmacology and Toxicology and Medical Research Center Oulu at the University of Oulu, Finland, is a distinguished researcher in the field of toxicology. His work primarily focuses on the metabolic profiling of various substances, drug-drug interactions, and the toxicokinetics and toxicodynamics of different chemicals. Pelkonen's research has substantial implications in regulatory pesticide risk assessment and the development of biomarkers of toxicity.

Research Contributions

Olavi R. Pelkonen has made significant contributions to toxicology, particularly in understanding the metabolism of various substances in mammalian systems. His recent work includes studies on the metabolic profiling and in vitro-in vivo extrapolation of furathiocarb in mammalian hepatic microsomes, and the characterization of its metabolism in human liver microsomes and recombinant cytochrome P450 enzymes. Pelkonen has also explored the role of animals in drug development within the context of in silico, in vitro, and in vivo human studies. Additionally, he has contributed to our understanding of CYP-associated drug-drug interactions, inhibition and induction of CYP enzymes, and the integration of epidemiological findings with mechanistic evidence in regulatory pesticide risk assessments.

Aliases

Olavi R. Pelkonen is also known by several aliases, including O. Pelkonen, Olavi Pelkonen, O Pelkonen, and Olavi R. Pelkonen.

Publication and Citation Metrics

Metric Value
Number of Papers 417
Citation Count 17,961
h-index 71

Publications:

DOI: 10.1007/s00204-020-02912-1

Year: 2020

DOI: 10.1007/s00204-020-02936-7

Year: 2020

DOI: 10.1016/b978-0-12-814655-2.00018-9

Year: 2019

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