Cholesterol is categorized into two main types: LDL (Low-Density Lipoprotein) and HDL (High-Density Lipoprotein). LDL is often referred to as "bad cholesterol" because high levels can lead to plaque buildup in arteries, increasing the risk of heart disease. HDL is known as "good cholesterol" as it helps remove LDL cholesterol from the bloodstream. Toxicological studies might focus on how substances affect either or both of these cholesterol types.