What is the Hen's Egg Test on the Chorioallantoic Membrane (HET-CAM)?
The Hen's Egg Test on the Chorioallantoic Membrane (HET-CAM) is an in vitro method used to assess the toxicity and irritation potential of chemicals, pharmaceuticals, cosmetics, and other substances. This test involves applying the test substance onto the chorioallantoic membrane (CAM) of a fertilized hen's egg and observing any adverse reactions. The CAM is a highly vascularized membrane that can mimic certain aspects of human tissue response.