Cyp450 Inhibitor - Toxicology

Relevant Publications

The discovery of a novel pyrrolo[2,3-b]pyridine as a selective CDK8 inhibitor offers a new approach against psoriasis.

Issue Release: 2024

Enhanced Herbicide Metabolism and Target Site Mutation Enabled the Multiple Resistance to Cyhalofop-butyl, Florpyrauxifen-benzyl, and Penoxsulam in .

Issue Release: 2024

Optimization of assay conditions to quantify ECOD activity in vivo in individual Daphnia magna. Assay performance evaluation with model CYP 450 inducers/inhibitors.

Issue Release: 2024

Safety and pharmacokinetics of antifungal agent VT-1598 and its primary metabolite, VT-11134, in healthy adult subjects: phase 1, first-in-Human, randomized, double-blind, placebo-controlled study of single-ascending oral doses of VT-1598.

Issue Release: 2024

Diverse ALS mutations and cross-and multiple-resistance to ALS and EPSPS inhibitors in flucarbazone‑sodium-resistant Bromus japonicus populations from Hebei province, China.

Issue Release: 2024

Synthesis of mono Cytochrome P450 in a modified CHO-CPR cell-free protein production platform.

Issue Release: 2024

The Cys-2088-Arg mutation in the ACCase gene and enhanced metabolism confer cyhalofop-butyl resistance in Chinese sprangletop (Leptochloa chinensis).

Issue Release: 2024

Proof-of-concept studies with a computationally designed M inhibitor as a synergistic combination regimen alternative to Paxlovid.

Issue Release: 2024

Polygala fallax Hemsl polysaccharides alleviated alcoholic fatty liver disease by modifying lipid metabolism via AMPK.

Issue Release: 2024

Effect of tubeimoside I on the activity of cytochrome P450 enzymes in human liver microsomes.

Issue Release: 2024

Paralytic ileus in a patient on clozapine therapy showing an inverted clozapine/norclozapine ratio after switching valproic acid to carbamazepine: a case report.

Issue Release: 2024

Distinctive physiological and molecular responses of foxtail millet and maize to nicosulfuron.

Issue Release: 2024

Tankyrase1/2 inhibitor XAV-939 reverts EMT and suggests that PARylation partially regulates aerobic activities in human hepatocytes and HepG2 cells.

Issue Release: 2024

Gal-1-mediated cytochrome p450 activation promotes fibroblast into myofibroblast differentiation in pulmonary fibrosis.

Issue Release: 2024

Scaffold hopping-driven optimization for the identification of NLRP3 inhibitors as potential gout therapeutics.

Issue Release: 2024

In Silico Drug Repurposing Studies for the Discovery of Novel Salicyl-AMP Ligase (MbtA)Inhibitors.

Issue Release: 2023

Pharmacokinetic Interactions Between Abiraterone, Apalutamide, Darolutamide or Enzalutamide and Antithrombotic Drugs: Prediction of Clinical Events and Review of Pharmacological Information.

Issue Release: 2023

Comparison and summary of in silico prediction tools for CYP450-mediated drug metabolism.

Issue Release: 2023

Role of genetic polymorphisms in clopidogrel response variability: a systematic review.

Issue Release: 2023

METTL3 exacerbates insulin resistance in hepatocytes by regulating mA modification of cytochrome P450 2B6.

Issue Release: 2023

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What Role Does Image Analysis Play?

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What are the Different Types of Exposure Dose?

How Can Abdominal Pain from Toxic Exposure Be Prevented?

How Can Toxin Exposure Be Prevented?

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Cyp450 Inhibitor - Toxicology

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