In Vitro And Computational Models - Toxicology

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Zurletrectinib is a next-generation TRK inhibitor with strong intracranial activity against NTRK fusion-positive tumours with on-target resistance to first-generation agents.

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Biomarkers of Cellular Senescence and Aging: Current State-of-the-Art, Challenges and Future Perspectives.

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Characterization of Induced Current Density During Transcorneal Electrical Stimulation to Promote Neuroprotection in the Degenerating Retina.

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A review of the use of numerical analysis in stomach modeling.

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Optimizing PGRs for in vitro shoot proliferation of pomegranate with bayesian-tuned ensemble stacking regression and NSGA-II: a comparative evaluation of machine learning models.

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Prediction of physicochemical and pharmacokinetic properties of botanical constituents by computational models.

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Using DFT on ultrasound measurements to determine patient-specific blood flow boundary conditions for computational hemodynamics of intracranial aneurysms.

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Molecular Mechanistic Insights into Dipeptidyl Peptidase-IV Inhibitory Peptides to Decipher the Structural Basis of Activity.

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Integrating Computational and Biological Hemodynamic Approaches to Improve Modeling of Atherosclerotic Arteries.

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A Multimodal Fitting Approach to Construct Single-Neuron Models with Patch Clamp and High-Density Microelectrode Arrays.

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Hepatic toxicity prediction of bisphenol analogs by machine learning strategy.

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HPC Framework for Performing in Silico Trials Using a 3D Virtual Human Cardiac Population as Means to Assess Drug-Induced Arrhythmic Risk.

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Ensemble-based design of tau to inhibit aggregation while preserving biological activity.

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Integrated drug response prediction models pinpoint repurposed drugs with effectiveness against rhabdomyosarcoma.

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A Fibrin-Thrombin Based In Vitro Perfusion System to Study Flow-Related Prosthetic Heart Valves Thrombosis.

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The rise of big data: deep sequencing-driven computational methods are transforming the landscape of synthetic antibody design.

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Dual Checkpoint Aptamer Immunotherapy: Unveiling Tailored Cancer Treatment Targeting CTLA-4 and NKG2A.

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Experimental and Computational Methods to Assess Central Nervous System Penetration of Small Molecules.

Issue Release: 2024

Integrating High-Resolution Mass Spectral Data, Bioassays and Computational Models to Annotate Bioactives in Botanical Extracts: Case Study Analysis of Extract Associates Dicaffeoylquinic Acids with Protection against Amyloid-β Toxicity.

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What Are the Potential Allergic Reactions to Lysozyme?

What are Emerging Methodologies?

Can Technetium 99m Contaminate the Environment?

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What is the Role of Regulation?

What Are the Toxicological Implications of Disrupted Meiosis?

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In Vitro And Computational Models - Toxicology

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