Methylxanthine Class - Toxicology

Relevant Publications

Theophylline reverses oxycodone\'s but not fentanyl\'s respiratory depression in mice while caffeine is ineffective against both opioids.

Issue Release: 2023

Caffeine improves memory and cognition via modulating neural progenitor cell survival and decreasing oxidative stress in Alzheimer\'s rat model.

Issue Release: 2023

Immunostimulatory Activities of Theobromine on Macrophages via the Activation of MAPK and NF-κB Signaling Pathways.

Issue Release: 2022

Functional modulation of phosphodiesterase-6 by calcium in mouse rod photoreceptors.

Issue Release: 2021

Elucidating the interaction of aminophylline with calf thymus DNA using multispectroscopic and molecular docking approach.

Issue Release: 2020

Inhibition of germinal vesicle breakdown using IBMX increases microRNA-21 in the porcine oocyte.

Issue Release: 2020

Unique Role of Caffeine Compared to Other Methylxanthines (Theobromine, Theophylline, Pentoxifylline, Propentofylline) in Regulation of AD Relevant Genes in Neuroblastoma SH-SY5Y Wild Type Cells.

Issue Release: 2020

Identification and characterization of oxidoreductase component (NdmD) of methylxanthine oxygenase system in Pseudomonas sp. NCIM 5235.

Issue Release: 2018

Xanthines Studied via Femtosecond Fluorescence Spectroscopy.

Issue Release: 2016

Caffeine and the analog CGS 15943 inhibit cancer cell growth by targeting the phosphoinositide 3-kinase/Akt pathway.

Issue Release: 2014

Novel, highly specific N-demethylases enable bacteria to live on caffeine and related purine alkaloids.

Issue Release: 2012

Notes on the history of caffeine use.

Issue Release: 2011

Methylxanthines in asthma.

Issue Release: 2011

cGMP phosphodiesterase inhibition improves the vascular and metabolic actions of insulin in skeletal muscle.

Issue Release: 2011

Botanical and geographical characterization of green coffee (Coffea arabica and Coffea canephora): chemometric evaluation of phenolic and methylxanthine contents.

Issue Release: 2009

A G alpha subunit gene is essential for conidiation and potassium efflux but dispensable for pathogenicity of Alternaria alternata on citrus.

Issue Release: 2009

Rapid changes of mRNA-binding protein levels following glucose and 3-isobutyl-1-methylxanthine stimulation of insulinoma INS-1 cells.

Issue Release: 2008

Crystal structure of the Leishmania major phosphodiesterase LmjPDEB1 and insight into the design of the parasite-selective inhibitors.

Issue Release: 2007

Hemorheological efficiency of drugs, targeting on intracellular phosphodiesterase activity: in vitro study.

Issue Release: 2007

Regulatory interactions of N1303K-CFTR and ENaC in Xenopus oocytes: evidence that chloride transport is not necessary for inhibition of ENaC.

Issue Release: 2006

What is Cysteine?

What Are the Advantages of Histochemical Techniques?

How Do Viral Infections Interact with Toxicology?

Are PELs the Same for All Substances?

How Do Mitochondria Respond to Toxic Exposure?

What Future Developments Can We Expect in Toxicology Simulations?

What Are the Challenges in Maintaining Confidentiality?

How is Physical Dependence Diagnosed?

How Do Concentration and Exposure Relate to Strength?

What is the Hunter Criteria?

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