Poly (adp Ribose) Polymerases (parp) - Toxicology

Relevant Publications

CHK1 inhibitor induced PARylation by targeting PARG causes excessive replication and metabolic stress and overcomes chemoresistance in ovarian cancer.

Issue Release: 2024

Deltex family E3 ligases specifically ubiquitinate the terminal ADP-ribose of poly(ADP-ribosyl)ation.

Issue Release: 2024

Predictive Value and Therapeutic Significance of Somatic BRCA Mutation in Solid Tumors.

Issue Release: 2024

Vesicular translocation of PARP-1 to cytoplasm causes ADP-ribosylation and disassembly of vimentin filaments during microglia activation induced by LPS.

Issue Release: 2024

Molecular mechanism of PARP inhibitor resistance.

Issue Release: 2024

Poly (ADP-ribose) polymerase-1 (PARP-1) is a good prognostic marker for pancreatic/periampullary cancers.

Issue Release: 2024

Patents on PARP-1 Inhibitors for the Management of Cancer from 2017-2023.

Issue Release: 2024

Anti-cancer effects of nitazoxanide in epithelial ovarian cancer in-vitro and in-vivo.

Issue Release: 2024

Poly-(ADP-ribose) polymerases inhibition by olaparib attenuates activities of the NLRP3 inflammasome and of NF-κB in THP-1 monocytes.

Issue Release: 2024

Pamiparib as consolidation treatment after concurrent chemoradiotherapy of limited-stage small cell lung cancer: a single-arm, open-label phase 2 trial.

Issue Release: 2024

Novel anti- effects elicited by a repurposed poly (ADP-ribose) polymerase inhibitor AZ9482.

Issue Release: 2024

The Ser/Thr protein kinase FonKin4-poly(ADP-ribose) polymerase FonPARP1 phosphorylation cascade is required for the pathogenicity of watermelon fusarium wilt fungus f. sp. .

Issue Release: 2024

Poly(ADP-Ribose) Polymerases-Inhibitor Talazoparib Inhibits Muscle Atrophy and Fatty Infiltration in a Tendon Release Infraspinatus Sheep Model: A Pilot Study.

Issue Release: 2024

The 5-WS of targeting DNA-damage repair (DDR) pathways in prostate cancer.

Issue Release: 2024

Nicotinamide Suppresses Hyperactivation of Dendritic Cells to Control Autoimmune Disease through PARP Dependent Signaling.

Issue Release: 2024

Strategies for the prevention or reversal of PARP inhibitor resistance.

Issue Release: 2024

Analysis of the mechanisms underlying the anticancer and biological activity of retinoic acid and chitosan nanoparticles containing retinoic acid.

Issue Release: 2024

Crocetin antagonizes parthanatos in ischemic stroke via inhibiting NOX2 and preserving mitochondrial hexokinase-I.

Issue Release: 2023

Regulation of Rad52-dependent replication fork recovery through serine ADP-ribosylation of PolD3.

Issue Release: 2023

Poly(ADP-ribose) polymerase-1 affects vasopressin-mediated AQP2 expression in collecting duct cells of the kidney.

Issue Release: 2023

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