Selective Pxr Modulators - Toxicology

Relevant Publications

Target Hopping from Protein Kinases to PXR: Identification of Small-Molecule Protein Kinase Inhibitors as Selective Modulators of Pregnane X Receptor from TüKIC Library.

Issue Release: 2022

Regulation of PXR Function by Coactivator and Corepressor Proteins: Ligand Binding Is Just the Beginning.

Issue Release: 2021

Garcinoic Acid Is a Natural and Selective Agonist of Pregnane X Receptor.

Issue Release: 2020

Pregnane X Receptor and Cancer: Context-Specificity is Key.

Issue Release: 2016

Characterization of ligand-dependent activation of bovine and pig constitutive androstane (CAR) and pregnane X receptors (PXR) with interspecies comparisons.

Issue Release: 2015

Marine sponge steroids as nuclear receptor ligands.

Issue Release: 2012

Pregnane xenobiotic receptor in cancer pathogenesis and therapeutic response.

Issue Release: 2012

Nuclear receptor drug discovery.

Issue Release: 2008

Can Humoral Immunity Be Enhanced for Better Toxicity Defense?

What is the Toxicological Significance of Natural Estrogens?

How is Lidocaine Metabolized?

How Do Organisms Regulate Osmotic Pressure in Response to Toxins?

How Are Haptens Related to the Concept of Sensitization?

What is Monitoring?

Are There Specific Populations at Greater Risk?

What is Immune Evasion?

What Factors Influence Excretion?

What Role Do Essential Minerals Play in Toxicology?

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