guangyu wu - Toxicology

Author Information

Guangyu Wu is a prominent researcher affiliated with the Department of Pharmacology and Toxicology at the Medical College of Georgia, Georgia Regents University, in Augusta, Georgia, USA. His extensive research work contributes significantly to the understanding of pharmacological and toxicological processes, particularly in the realm of G protein-coupled receptors and their implications in various diseases.

Research Contributions

Guangyu Wu has made substantial contributions to the field of pharmacology and toxicology, focusing on the intricate mechanisms of G protein-coupled receptors (GPCRs). His research explores the physiological and pathological roles of these receptors, including their surface transport and signaling pathways. Notable topics in his work include the post-synaptic transport of GPCRs, the role of β-arrestins in Parkinson's disease, and the impact of compounds like lithium chloride on axonal transport in neurons. His studies often involve advanced methodologies such as live-cell radioligand binding assays and provide critical insights into therapeutic strategies for conditions like diabetes mellitus and neurodegenerative diseases.

Aliases

There are no aliases provided for Guangyu Wu, suggesting that he publishes under his full name consistently.

Publication and Citation Metrics

Metric	Value
Citation Count	5694
H-index	40
Paper Count	129

Publications:

Specific motifs mediate post-synaptic and surface transport of G protein-coupled receptors

DOI: 10.1016/j.isci.2021.103643

Year: 2022

Efficacy of once‐daily glucagon‐like peptide‐1 receptor agonist lixisenatide as an add‐on treatment to basal insulin in Asian and white adults with type 2 diabetes mellitus: An individual‐level pooled analysis of phase III studies

DOI: 10.1111/jdi.13504

Year: 2021

Opposing functions of β-arrestin 1 and 2 in Parkinson’s disease via microglia inflammation and Nprl3

DOI: 10.1038/s41418-020-00704-9

Year: 2021

Corrigendum to "Multifunctional compounds lithium chloride and methylene Blue attenuate the negative effects of diisopropylfluorophosphate on axonal transport in rat cortical neurons" [Toxicology 431 (2020): 152379].

DOI: 10.1016/j.tox.2021.152745

Year: 2021

Rab43 GTPase directs postsynaptic trafficking and neuron-specific sorting of G protein–coupled receptors

DOI: 10.1016/j.jbc.2021.100517

Year: 2021

G protein βγ translocation to the Golgi apparatus activates MAPK via p110γ-p101 heterodimers

DOI: 10.1016/j.jbc.2021.100325

Year: 2021

Gβγ translocation to the Golgi apparatus activates ARF1 to spatiotemporally regulate G protein–coupled receptor signaling to MAPK

DOI: 10.1016/j.jbc.2021.100805

Year: 2021

The Carbamate, Physostigmine does not Impair Axonal Transport in Rat Cortical Neurons

DOI: 10.1177/26331055211020289

Year: 2021

Quantification of The Surface Expression of G Protein-coupled Receptors Using Intact Live-cell Radioligand Binding Assays.

DOI: 10.21769/BIOPROTOC.3761

Year: 2020

Dissection of anterograde trafficking and sorting of GPCRs in primary neurons

DOI: 10.1096/fasebj.2020.34.s1.04122

Year: 2020

How Do Toxins Interact with Biological Targets?

What Factors Increase the Risk of Statin Toxicity?

What Role Does Toxicology Play in the Treatment of Heart Attacks?

How Does Chemical Exposure Affect the Mapt Gene?

How Do Environmental Toxins Affect Human Health?

How is Exposure to Non-Ionizing Radiation Measured?

How Do Ambulances Handle Toxicological Emergencies?

What Is the Role of Toxicology in Fragrance Safety?

What Are Biomarkers in Molecular Toxicology?

What is the Future Direction of Research?

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