Sten Orrenius - Toxicology

Author Information

Sten Orrenius is affiliated with the Institute of Environmental Medicine at the Karolinska Institutet, located in Stockholm, Sweden. His research primarily focuses on the mechanisms of cell death, including the roles of mitochondria, calcium, and reactive oxygen species in these processes. His work has significant implications for understanding toxicology and pharmacology.

Research Contributions

Sten Orrenius has made substantial contributions to the field of toxicology, particularly in understanding the mechanisms of cell death. His research explores various aspects of cell death, such as mitochondrial dysfunction, the role of calcium, and the impact of reactive oxygen species. Notable studies include examining the switchboard role of mitochondria in cell death modalities, the regulation of cell death by calcium and mitochondria, and the targeting of hepatoma using nitric oxide donor strategies. His work also delves into the interplay between autophagy and toxicology, as well as the degradation of cytoskeleton proteins during apoptotic cell death.

Aliases

Sten Orrenius is also known by several aliases in academic publications, including S G Orrenius, S Orrenius, and S. Orrenius.

Publication and Citation Metrics

Metric Value
Citation Count 56,162
H-Index 126
Paper Count 542

Publications:

DOI: 10.1146/annurev-pharmtox-010818-021725

Year: 2019

DOI: 10.1007/978-1-4939-2257-4_33

Year: 2015

DOI: 10.1016/j.bbrc.2015.01.137

Year: 2015

DOI: 10.1089/ars.2011.4476

Year: 2013

DOI: 10.1146/annurev-pharmtox-011112-140210

Year: 2013