Ladybugs can be mildly toxic to pets if ingested in large quantities. The same alkaloids that protect ladybugs from predators can cause gastrointestinal distress in animals such as dogs and cats, leading to symptoms like vomiting or diarrhea. However, these occurrences are rare and generally not life-threatening. It is advisable to monitor pets that have ingested ladybugs and consult a veterinarian if symptoms develop.