Are Morphological Changes Specific to Certain Toxicants?
Some morphological changes may be relatively specific to certain classes of toxicants, serving as biomarkers of exposure. For instance, vacuolation of cells is a hallmark of exposure to certain solvents, while the presence of Mallory bodies in the liver is indicative of alcohol-induced damage. However, many changes, like necrosis and inflammation, are non-specific and can result from a variety of toxic insults.
