Are Prions Resistant to Traditional Decontamination Methods?
Yes, prions are notoriously resistant to conventional decontamination methods that are effective against other pathogens. They withstand common disinfectants, heat, and even standard autoclaving. This resistance necessitates stringent measures for decontamination, such as prolonged exposure to high temperatures in combination with chemical treatments like sodium hydroxide or hypochlorite solutions. This resistance poses significant challenges in healthcare settings, particularly concerning the reuse of surgical instruments.
