Can Carcinogen Metabolism be Modified to Reduce Cancer Risk?
There is ongoing research into ways to modify carcinogen metabolism to reduce cancer risk. This includes dietary interventions, such as increasing the intake of cruciferous vegetables, which are known to induce Phase II detoxification enzymes. Additionally, pharmaceuticals that modulate enzyme activity are being explored as potential chemopreventive agents. Understanding the balance between activation and detoxification of carcinogens is key to these strategies.