Can Cyclins Serve as Biomarkers for Toxic Exposure?
Yes, cyclins can serve as biomarkers for toxic exposure. Changes in cyclin levels can indicate exposure to toxic agents and may reflect early cellular responses to such exposure. For example, increased levels of cyclin D1 have been reported in liver cells upon exposure to certain hepatotoxins, making it a potential biomarker for liver damage. Monitoring cyclin levels can therefore be useful in assessing the impact of toxic substances on cell cycle regulation.