Can Environmental Exposures Affect BRCA1 Function?
Yes, environmental exposures to certain chemical agents and ionizing radiation can impair BRCA1 function. For instance, exposure to polycyclic aromatic hydrocarbons (PAHs) and other carcinogens can induce DNA damage that requires efficient repair mechanisms. If BRCA1 function is compromised, such exposures could lead to an increased risk of cancer development.
