Can Infections Alter the Toxicokinetics of Substances?
Yes, infections can significantly impact the toxicokinetics of substances. During an infection, the body's metabolic rate may change, affecting how toxins are absorbed, distributed, metabolized, and excreted. For instance, fever can increase metabolic rates, potentially accelerating the metabolism of certain drugs and toxins, while liver infections might impair the body's ability to detoxify certain chemicals.
