Can LDH Levels Differentiate Between Different Types of Tissue Damage?
While LDH is a valuable marker for tissue damage, it is not specific to any one type of tissue or organ. However, the distribution of LDH isoenzymes can provide more specific information. LDH exists in five isoenzyme forms, which vary in their tissue distribution. For instance, LDH-1 is predominant in the heart and red blood cells, while LDH-5 is more common in the liver and skeletal muscles. Analyzing the pattern of LDH isoenzymes can help pinpoint the source of tissue damage.
