Can Mapt Gene Variants Influence Susceptibility to Toxicants?
Genetic variations in the Mapt gene can affect an individual's susceptibility to environmental toxins. Certain single nucleotide polymorphisms (SNPs) in the Mapt gene have been associated with increased risk of developing tauopathies upon exposure to neurotoxicants. Research is ongoing to identify specific Mapt gene variants that may confer heightened vulnerability to chemical-induced neurodegeneration.
