The determination of acceptable exposure levels involves a comprehensive risk assessment process. This includes:
Hazard Identification: Identifying the potential adverse effects associated with a substance. Exposure Assessment: Estimating the magnitude, frequency, and duration of human exposure to the substance. Dosage-Response Assessment: Evaluating the relationship between the exposure level and the severity of the adverse effects. Risk Characterization: Integrating information from the previous steps to estimate the potential health risks.
Regulatory agencies, such as the EPA and the ECHA, use this information to establish guidelines and standards for safe exposure levels.