Management of antidepressant toxicity depends on the type and severity of the symptoms:
Supportive Care: This includes stabilizing vital signs, ensuring airway protection, and providing intravenous fluids. Activated Charcoal: Administered within a few hours of ingestion to limit absorption. Antidotes: While no specific antidotes exist for most antidepressants, benzodiazepines are used to manage seizures, and sodium bicarbonate may be used in TCA overdose to treat cardiac arrhythmias. Serotonin Antagonists: Medications like cyproheptadine can be used to counteract serotonin syndrome.