To reduce the likelihood of false positives, several steps can be taken: - Confirmatory Testing: Utilizing a second, more specific test such as Gas Chromatography-Mass Spectrometry (GC-MS) to confirm initial positive results. - Proper Sample Handling: Ensuring samples are collected, stored, and processed correctly to minimize contamination. - Thorough History: Obtaining a comprehensive history of the patient’s medication and dietary intake. - Advanced Assays: Employing more sophisticated and specific assays to reduce cross-reactivity.