Aquifers are underground layers of water-bearing rock, essential for supplying drinking water, irrigation, and industrial needs. In toxicology, aquifers are significant because they can become contaminated by chemical spills, agricultural chemicals, or inadequate waste disposal. Once polluted, an aquifer can be extremely challenging to clean, making it imperative to understand how toxins can infiltrate these water sources. Contaminated aquifers can lead to long-term health issues, such as cancer and reproductive problems, when the polluted water is used for drinking or irrigation.