Toxicokinetics, the study of how a substance enters, moves through, and exits the body, is significantly influenced by biological rhythms. For instance, the absorption, distribution, metabolism, and excretion (ADME) of toxins can vary depending on the time of day. The liver's metabolic activity, which plays a key role in detoxification, fluctuates with the circadian cycle, affecting how quickly and efficiently toxins are broken down.
