Regulatory frameworks for toxic substances vary significantly across the globe. In high-income countries, there are stringent regulations and robust regulatory bodies such as the Environmental Protection Agency (EPA) in the United States and the European Chemicals Agency (ECHA) in the European Union. These entities have the resources to conduct detailed assessments and enforce compliance.
Conversely, many low and middle-income countries have less stringent regulations and fewer resources to monitor and manage chemical safety. This discrepancy can lead to a higher prevalence of toxic exposure and associated health risks in these regions.