Cellular communication is vital for maintaining tissue homeostasis and function. Toxicants can disrupt communication by altering gap junctions, affecting paracrine signaling, or modifying extracellular matrix interactions. For example, heavy metals like lead can inhibit gap junction communication, leading to impaired tissue function and development. Understanding these effects can aid in identifying biomarkers for toxicant exposure and developing targeted therapies.
In conclusion, cellular processes are at the heart of toxicology, providing insights into how toxicants cause harm and how cells respond to these challenges. By understanding these processes, toxicologists can better assess risks, design safer chemicals, and develop therapeutic strategies to mitigate toxic effects.
