Certain toxicants can accelerate plaque formation or exacerbate their effects. Heavy metals like lead and mercury can enhance oxidative stress, promoting the development of amyloid plaques in the brain. Persistent organic pollutants such as dioxins and PCBs can disrupt lipid metabolism, leading to increased cholesterol plaque formation in arteries. Studying these interactions helps in identifying environmental and occupational risks associated with plaque-related diseases.
