Toxins can impact electrolyte balance in numerous ways. They might cause the body to lose excessive fluids through vomiting, diarrhea, or increased urination, leading to the loss of important electrolytes. Certain poisons and drugs can directly affect kidney function, altering the body's ability to retain or excrete electrolytes. For example, heavy metals like lead and mercury can impair renal function, thereby disrupting electrolyte homeostasis.