Several toxins and medications can interfere with the body's natural ability to regulate blood pressure. For instance, substances that affect the autonomic nervous system, such as some antidepressants and antihypertensive drugs, can lead to orthostatic hypotension. These chemicals may alter the function of the baroreceptors, which are sensors in the cardiovascular system that help maintain stable blood pressure. Additionally, toxins that cause dehydration or reduce blood volume, like alcohol or diuretics, can also contribute to this condition.
