The route of exposure is a key determinant of how efficiently a toxin is taken up by the body. For instance, inhalation allows for rapid uptake through the lungs due to their large surface area and extensive blood supply. In contrast, dermal uptake may be slower unless the substance is highly lipophilic and can easily penetrate the skin. Ingestion involves uptake through the gastrointestinal tract, where factors like the presence of food can affect absorption rates.
