The vomiting center receives input from several sources that detect toxins. One of the primary pathways is through the chemoreceptor trigger zone (CTZ), which is located adjacent to the vomiting center. The CTZ can detect circulating toxins in the blood and cerebrospinal fluid due to its location outside the blood-brain barrier. Other inputs come from the gastrointestinal tract, vestibular system, and higher brain centers, which can all signal the presence of noxious agents.
