Toxic exposure can disrupt normal hormonal pathways, leading to endocrine disorders like CDI. For example, substances such as lithium, a medication often used for bipolar disorder, can interfere with kidney response to ADH, potentially leading to diabetes insipidus. Furthermore, certain heavy metals and solvents might also contribute to pituitary dysfunction if exposure is significant. Recognizing these toxicological factors is crucial in both preventing and treating CDI.
