How is ADMET Prediction Integrated into Drug Development?
In the drug development pipeline, ADMET prediction is integrated at various stages:
Lead Optimization: It helps in refining chemical structures to enhance desirable properties while minimizing toxicity. Preclinical Testing: Predictions guide the design of in vitro and in vivo experiments to validate safety and efficacy. Regulatory Submissions: Data from ADMET predictions can support regulatory submissions by demonstrating a compound's safety profile.
