How is Aneuploidy Detected in Toxicological Studies?
Detection of aneuploidy in toxicological studies typically involves cytogenetic assays such as the micronucleus test, which assesses the presence of micronuclei in cells as a marker of chromosomal instability. Another common method is fluorescence in situ hybridization (FISH), which uses fluorescent probes to identify specific chromosomes or chromosome segments, allowing researchers to detect numerical changes in chromosome sets.
