Oxidative stress refers to the imbalance between free radicals and antioxidants in the body, leading to cellular damage. Cholesterol, particularly LDL, can undergo oxidation, forming oxidized LDL (oxLDL). OxLDL is highly atherogenic and contributes to the formation of plaques in arteries. The toxicological implications of oxidative stress and cholesterol oxidation are significant in the context of cardiovascular diseases.
