Genotoxicity testing is an essential part of evaluating the safety of chemicals and drugs. Various assays are used to detect genotoxic effects, including the Ames test, which assesses mutations in bacteria, and the Comet assay, which evaluates DNA strand breaks in eukaryotic cells. Other tests, such as the micronucleus test, help identify chromosomal damage. These assays provide critical data for risk assessment and regulatory purposes.