Toxicologists assess immunosuppression through various methods, including in vivo and in vitro studies. Animal models are often used to evaluate the effects of chemicals on the immune system, while cell-based assays can help identify specific mechanisms of action. Biomarkers, such as changes in white blood cell counts or cytokine levels, are also employed to assess immune function. Regulatory agencies often require immunotoxicity testing for chemicals and pharmaceuticals to ensure safety.