How is Maximum Response Used in Toxicological Evaluations?
In toxicological evaluations, the maximum response is used to:
Determine the threshold level: Below which no significant effect is observed. Establish acceptable daily intake (ADI): For substances such as food additives and contaminants. Calculate the effective dose 50 (ED50): The dose required to achieve 50% of the maximum response. Assess the toxicity potential: For new chemicals and pharmaceuticals.
