In toxicology, NMF can be applied in various ways:
Exposure Assessment: NMF can help decompose complex exposure data into interpretable patterns, identifying different source contributions and their temporal variations. Biomarker Discovery: By analyzing omics data, such as genomics or proteomics, NMF can help identify potential biomarkers of exposure or effect. Mixture Toxicology: It assists in understanding the combined effects of multiple chemicals in a mixture, which is a common scenario in real-world toxicology.