p53 tumor suppressor

How is p53 Studied in Toxicology Research?

In toxicology research, p53 is often studied using cell lines or animal models that have been genetically modified to either lack p53 or express mutant forms of the protein. These models help researchers understand how different substances affect p53's activity and the downstream cellular responses. Additionally, p53-targeted assays are used to evaluate the genotoxic potential of new chemicals and drugs.

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