How is the Key-Lock Concept Applied in Antidote Development?
The development of antidotes often relies on the key-lock principle. Antidotes are designed to either displace a toxicant from its biological target or to prevent its binding. For example, naloxone acts as an antidote for opioid overdose by competitively binding to opioid receptors, displacing the opioid and reversing its effects. This competitive binding is a direct application of the key-lock theory.
