The body has several mechanisms to regulate trypsin activity to prevent toxic effects. One of the primary means of regulation is through trypsin inhibitors, which are proteins that bind to trypsin and prevent it from degrading proteins indiscriminately. Additionally, trypsin is synthesized as an inactive precursor called trypsinogen. It is only converted to its active form in the small intestine by enterokinase, thus limiting its activity to the appropriate site.
