Choosing the appropriate sample preparation method depends on several factors:
Analyte Properties: Understanding the chemical properties of the analytes is essential for selecting a method that will effectively isolate and detect them. Sample Matrix: The complexity of the sample matrix can dictate the choice of preparation method. More complex matrices may require multi-step processes. Detection Requirements: The sensitivity and selectivity required for the analysis will influence the choice of sample preparation technique. Cost and Time: Budgetary constraints and time limitations can also impact method selection, especially in high-throughput environments.