Thiocyanate itself is generally considered to be of low toxicity compared to its precursor, cyanide. However, at high concentrations, it can interfere with iodine uptake in the thyroid gland, leading to potential disruptions in thyroid hormone production. This can cause goiter and hypothyroidism, particularly in populations with low iodine intake. The toxic effects of thiocyanate are more pronounced when iodine deficiency is present.